ISOLATION OF A HUMAN CEREBRAL IMIDAZOLINE-SPECIFIC BINDING-PROTEIN

Authors
GRENEY H BENNAI F MOLINES A BELCOURT A DONTENWILL M BOUSQUET P
Citation
H. Greney et al., ISOLATION OF A HUMAN CEREBRAL IMIDAZOLINE-SPECIFIC BINDING-PROTEIN, European journal of pharmacology, 265(1-2), 1994, pp. 180000001-180000002
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
European journal of pharmacology → ACNP
ISSN journal
00142999
Volume
265
Issue
1-2
Year of publication
1994
Pages
180000001 - 180000002
Database
ISI
SICI code
0014-2999(1994)265:1-2<180000001:IOAHCI>2.0.ZU;2-H
Abstract
The first isolation of a human brain specific imidazoline binding prot ein is described. This protein was obtained using affinity chromatogra phy and was revealed with the aid of an anti-idiotypic antibody specif ic for imidazoline binding sites. The protein (43 kDa) differs from ot her imidazoline binding proteins previously isolated from peripheral t issues, in particular by being also sensitive to clonidine.