Authors
Citation
Ja. Jacquez, PARAMETER IDENTIFIABILITY IS REQUIRED IN POOLED DATA METHODS, Journal of pharmacokinetics and biopharmaceutics, 24(3), 1996, pp. 301-305
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
ISSN journal
0090466X
Volume
24
Issue
3
Year of publication
1996
Pages
301 - 305
Database
ISI
SICI code
0090-466X(1996)24:3<301:PIIRIP>2.0.ZU;2-E
Abstract
In pooled data methods such as naive pooled data methods and NONMEM, t
he number of sample points per individual may be less than the number
of unknown parameters so that the values of the parameters are not est
imable in individuals. However, for the moments of the distributions o
f the parameters to be estimable, the basic parameters must be identif
iable.