INFLUENCE OF DILANTIN OF REACTIONS OF NEU RONS OF THE SENSORIMOTOR CORTEX AND HIPPOCAMPUS DURING LEARNING

After dilantin (D) administration in a dose which reduced posttetanic potentiation (according to the data of literature), probability of mov ements to light flashes (conditioned signal of a defensive reflex) did not change. Weak but stable disinhibition of motor reactions to flash es was observed when they were presented at the background of continuo us light as a conditioned inhibitor. Activation of neurons of the sens orimotor cortex in response to reinforced and non-reinforced light fla shes increased under D action (as it had been earlier observed in neur ons of the visual cortex), and activatory reactions to pain reinforcem ent decreased. In hippocampal neurons increase of the rate of impulsat ion in response to reinforced flashes under the action of D disappeare d. On the basis of the data obtained it can be concluded that PTP in t he neocortex does not participate in long-term memory storage of the b iological significance of activating stimulus.