PLASTICITY OF CHOLINORECEPTORS ON HELIX-L UCORUM NEURONS AFTER THE ACTION ON INOSITOL-1,4,5-TRISPHOSPHATE-DEPENDENT AND CA2-DEPENDENT MOBILIZATION OF CA2+ AND PHOSPHATIDIC-ACID LEVEL()

Authors
PIVOVAROV AS
Citation
As. Pivovarov, PLASTICITY OF CHOLINORECEPTORS ON HELIX-L UCORUM NEURONS AFTER THE ACTION ON INOSITOL-1,4,5-TRISPHOSPHATE-DEPENDENT AND CA2-DEPENDENT MOBILIZATION OF CA2+ AND PHOSPHATIDIC-ACID LEVEL(), Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 44(4-5), 1994, pp. 796-805
Citations number
25
Categorie Soggetti
Physiology,Neurosciences
Journal title
Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova → ACNP
ISSN journal
00444677
Volume
44
Issue
4-5
Year of publication
1994
Pages
796 - 805
Database
ISI
SICI code
0044-4677(1994)44:4-5<796:POCOHU>2.0.ZU;2-B
Abstract
Effects of some substances (which influence on mobilization of deporte d Ca2+ and intracellular level of second messengers) on identified neu rons RPa3 and LPa3 of Helix lucorum were studied using two-electrode v oltage clamp technique. The action of inositol-1,4,5-trisphosphate (IP 3), inositolhexakisphosphate (IP6), TMB-8 (inhibitor of IP3-dependent Ca2+ mobilization), tetracaine (inhibitor of Ca2+-dependent mobilizati on of Ca2+), and phospholipase D (which catalizes phosphatidic acid fo rmation from membrane phosphatidylcholine) was studied. Participation of IP3, IP3-dependent-, Ca2+-dependent mobilized intracellular Ca2+ an d phosphatidic acid in regulation of cholinoreceptor plasticity was sh own in Helix neurons.