BACKGROUND. Biopsy of mucosal lesions can be carried out by means of s
everal methods. OBJECTIVE. To describe a combination technique for the
biopsy of mucosal lesions. METHODS. The combined effect of a chalazio
n forceps with a 4-mm punch allows the physicians to work on a stabili
zed, bloodless, and therefore simplified field. RESULTS. A preliminary
suture with a 4-0 catgut chromic is the key step in assuring a safe p
ost-operative hemostasis. CONCLUSION. This technique allows us to perf
orm accurate and safe oral mucosal biopsies without any major side eff
ects.