FIRST REGIOSELECTIVE MUCOR-MIEHEI LIPASE-CATALYZED SYNTHESIS OF DIESTER CROWNS - NEW MACROCYCLES CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT

Authors
FIERROS M RODRIGUEZFRANCO MI NAVARRO P CONDE S
Citation
M. Fierros et al., FIRST REGIOSELECTIVE MUCOR-MIEHEI LIPASE-CATALYZED SYNTHESIS OF DIESTER CROWNS - NEW MACROCYCLES CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT, Bioorganic & medicinal chemistry letters, 4(21), 1994, pp. 2523-2526
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
21
Year of publication
1994
Pages
2523 - 2526
Database
ISI
SICI code
0960-894X(1994)4:21<2523:FRMLSO>2.0.ZU;2-S
Abstract
Diester crowns 4a-c have been prepared for the first time by regiosele ctive lipase-catalyzed transesterification. The synthesized new ester crowns include a 1,3-bis(1H-pyrazol-1-yl)propane unit as a part of the macrocycle. Acyclic intermediates 3a-c were also obtained.