Ec. Orton et al., DYNAMIC CARDIOMYOPLASTY FOR TREATMENT OF IDIOPATHIC DILATATIVE CARDIOMYOPATHY IN A DOG, Journal of the American Veterinary Medical Association, 205(10), 1994, pp. 1415-1419
In a dog with advanced dilatative cardiomyopathy, dynamic cardiomyopla
sty resulted in improvement in clinical status and systolic function.
Dynamic cardiomyoplasty involved surgical isolation of the right latis
simus dorsi muscle on its neurovascular pedicle, transposition of the
muscle into the thoracic cavity, wrapping the ventricles with the musc
le, and implantation of a myostimulator for cardiosynchronous stimulat
ion of the muscle. After a 2-week period, the latissimus muscle underw
ent a 50-day period of progressive burst stimulation to transform the
muscle to a fatigue resistant phenotype. Thereafter, the muscle receiv
ed cardiosynchronous stimulation at a 3:1 R-wave-to-burst ratio. This
procedure may offer hope for long-term treatment of dilatative cardiom
yopathy in dogs.