LONG-TERM SEDATION WITH PROPOFOL AND GREEN DISCOLORATION OF THE LIVER

Authors
MOTSCH J SCHMIDTK H BACH A BOTTIGER BW BOHRER H
Citation
J. Motsch et al., LONG-TERM SEDATION WITH PROPOFOL AND GREEN DISCOLORATION OF THE LIVER, European journal of anaesthesiology, 11(6), 1994, pp. 499-502
Citations number
NO
Categorie Soggetti
Anesthesiology
Journal title
European journal of anaesthesiology → ACNP
ISSN journal
02650215
Volume
11
Issue
6
Year of publication
1994
Pages
499 - 502
Database
ISI
SICI code
0265-0215(1994)11:6<499:LSWPAG>2.0.ZU;2-T
Abstract
Propofol has been reported to cause discolouration of urine and hair. A case of green discolouration of the liver is reported in a 56-year-o ld man after long-term sedation with propofol in the intensive care un it. After discontinuation of propofol the discolouration of the liver disappeared. This phenomenon is due to metabolism of propofol which ma y lead to a phenolic green chromophore which is conjugated in the live r and excreted in the urine.