SYNTHESIS AND ANTIFUNGAL ACTIVITY OF ANALOGS OF NATURALLY-OCCURRING BOTRYDIAL PRECURSORS

Authors
COLLADO IG ALEU J MACIASSANCHEZ AJ HERNANDEZGALAN R
Citation
Ig. Collado et al., SYNTHESIS AND ANTIFUNGAL ACTIVITY OF ANALOGS OF NATURALLY-OCCURRING BOTRYDIAL PRECURSORS, Journal of chemical ecology, 20(10), 1994, pp. 2631-2644
Citations number
19
Categorie Soggetti
Ecology,Biology
Journal title
Journal of chemical ecology → ACNP
ISSN journal
00980331
Volume
20
Issue
10
Year of publication
1994
Pages
2631 - 2644
Database
ISI
SICI code
0098-0331(1994)20:10<2631:SAAAOA>2.0.ZU;2-9
Abstract
Analog compounds of the proposed intermediates of the biogenetic pathw ay to botrydial have been synthesized. These compounds were tested for their potential antifungal activity against the phytopathogen Botryti s cinerea. Our results showed a fungistatic effect of some compounds o n mycelium growth. The most significant effect was exerted by 2-alpha- hydroxy-2,3-dihydro-1-epiprobotrydial, which inhibited growth of B. ci nerea. Some aspects of structure-activity relationships are discussed.