The quality of volume-localized magnetic resonance spectroscopy is aff
ected by eddy currents caused by gradient switching. Eddy currents can
be reduced with improved gradient systems; however, it has been sugge
sted that the distortion due to eddy currents can be compensated for d
uring postprocessing with a single-frequency reference signal. The aut
hors propose modifying current techniques for acquiring the single-fre
quency reference signal by using relaxation weighting to reduce interf
erence from components that cannot be eliminated by digital filtering
alone. Additional sequences with T1 or T2 weighting for reference sign
al acquisition are shown to have the same eddy current characteristics
as the original signal without relaxation weighting. The authors also
studied a new eddy current correction method that does not require a
single-frequency reference signal. This method uses two free induction
decays (FIDs) collected from the same volume with two sequences with
opposite gradients. Phase errors caused by eddy currents are opposite
in these two FIDs and can be canceled completely by combining the FIDs
. These methods were tested in a phantom. Eddy current distortions wer
e corrected, allowing quantitative measurement of structures such as t
he -CH=CH- component, which is otherwise undetectable.