Background Cardiac tamponade frequently complicates acute proximal aor
tic dissection and is one of the most common causes of death from aort
ic dissection. Well-defined strategies for the management of acute aor
tic dissection now exist; however, little is known about how best to m
anage the hemopericardium that may complicate it. Methods and Results
Using a computer-based review, we retrospectively identified 10 patien
ts presenting to our hospital over a 13-year period who were diagnosed
with both aortic dissection and cardiac tamponade. All 10 had proxima
l dissections. Three of the 10 presented as the sudden onset of fatal
electromechanical dissociation, 6 presented with hypotension, and 1 wa
s normotensive on presentation. Of the 7 hypotensive or normotensive p
atients diagnosed with cardiac tamponade, 4 underwent successful peric
ardiocentesis while awaiting surgery. At time intervals of 5 to 40 min
utes after their pericardiocenteses, 3 of the 4 patients experienced s
udden onset of electromechanical dissociation and death; the fourth pa
tient survived and underwent surgical repair. Of the 3 hypotensive or
normotensive patients who had either no pericardiocentesis or an unsuc
cessful pericardiocentesis, all 3 underwent successful surgical repair
and survived. Conclusions In this study, patients with an aortic diss
ection complicated by cardiac tamponade have an early mortality of 60%
. While 3 of the 10 died from electromechanical dissociation immediate
ly upon presentation, the 3 other deaths all occurred shortly after su
ccessful pericardiocentesis, a procedure undertaken to stabilize them.
While the number of patients in this series is small, the observation
s do raise the possibility that in patients with cardiac tamponade com
plicating aortic dissection pericardiocentesis could be harmful rather
than beneficial. Possible mechanisms for why the performance of peric
ardiocentesis might destabilize such patients are proposed.