Objective: To evaluate changes in cervical dimensions by transvaginal
ultrasound in non-randomly selected pregnant women. Methods: This long
itudinal study included 154 pregnant women undergoing transvaginal ult
rasound assessment of the cervix at a mean gestational age of 12, 16,
20, 25, and 31 weeks. On each occasion, the longitudinal and anteropos
terior diameters of the cenix were measured. The rate of prematurity i
n the series was 1.9%, and the mean gestational age at delivery was 38
.7 weeks. Results: Overall, cervical length (mean 4.3 cm; 95% confiden
ce interval 4.1-4.3) did not change significantly (P = .06), whereas t
he anteroposterior diameter of the cervix at its midportion shortened
throughout the investigated period of gestation. Multiparous women had
longer and thicker cervices than primigravidas or women with previous
cesareans or first-trimester abortions. Gestational age at delivery d
id not correlate with cervical dimensions at any stage of pregnancy. C
onclusions: The cervix undergoes a change in shape from cylindrical to
conic, more marked in primigravidas than in parous women. Women who h
ad previous cesarean deliveries had cervical characteristics similar t
o primigravidas; therefore, it appears that mechanical, rather than ho
rmonal, factors have a greater effect in determining changes of cervic
al dimensions throughout pregnancy.