The authors describe an 11-year-old boy who had persistent oral lesion
s that clinically mimicked first-episode herpetic stomatitis. A biopsy
revealed noncaseating sterile granulomas. Investigation of the small
and large bowels revealed that the child had Crohn's disease. The oral
lesions responded favorably to topical steroid therapy. The authors a
lso discuss the range of oral lesions in inflammatory bowel disease an
d the differential diagnoses.