SYNTHESIS OF THE GUAIANE (+ -)-ALISMOL USING A FREE-RADICAL FRAGMENTATION/ELIMINATION SEQUENCE/

Authors
LANGE GL GOTTARDO C
Citation
Gl. Lange et C. Gottardo, SYNTHESIS OF THE GUAIANE (+ -)-ALISMOL USING A FREE-RADICAL FRAGMENTATION/ELIMINATION SEQUENCE/, Tetrahedron letters, 35(46), 1994, pp. 8513-8516
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
46
Year of publication
1994
Pages
8513 - 8516
Database
ISI
SICI code
0040-4039(1994)35:46<8513:SOTG(->2.0.ZU;2-W
Abstract
The first synthesis of the guaiane alismol (3) is reported. The effici ent, stereoselective and regioselective approach involves only eight s teps, with the key transformation being a radical fragmentation/elimin ation sequence-which proceeds in high yield (92%).