DIETHOXY N,N-DIISOPROPYL PHOSPHORAMIDITE AS AN IMPROVED CAPPING REAGENT IN THE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORAMIDITE CHEMISTRY

Authors
YU D TANG JY IYER RP AGRAWAL S
Citation
D. Yu et al., DIETHOXY N,N-DIISOPROPYL PHOSPHORAMIDITE AS AN IMPROVED CAPPING REAGENT IN THE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORAMIDITE CHEMISTRY, Tetrahedron letters, 35(46), 1994, pp. 8565-8568
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
46
Year of publication
1994
Pages
8565 - 8568
Database
ISI
SICI code
0040-4039(1994)35:46<8565:DNPAAI>2.0.ZU;2-O
Abstract
The use of diethoxy N, N-diisopropyl phosphoramidite (DDP) as a cappin g reagent for the synthesis of oligonucleotides, in conjunction with p hosphoramidite chemistry, results in overall improvement in quality an d yield.