SYNTHESIS AND CONFORMATIONAL BEHAVIOR OF NOVEL CYCLODEXTRIN HETERO-DIMERS

Authors
VENEMA F BASELIER CM FEITERS MC NOLTE RJM
Citation
F. Venema et al., SYNTHESIS AND CONFORMATIONAL BEHAVIOR OF NOVEL CYCLODEXTRIN HETERO-DIMERS, Tetrahedron letters, 35(46), 1994, pp. 8661-8664
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
46
Year of publication
1994
Pages
8661 - 8664
Database
ISI
SICI code
0040-4039(1994)35:46<8661:SACBON>2.0.ZU;2-W
Abstract
The synthesis of two novel cyclodextrin heterodimers derived from alph a- and beta-cyclodextrin is reported. The cyclodextrin molecules are l inked via alkyl spacers on their secondary sides. NMR-studies indicate that the spacer is bound in one of the two cavities of the dimer, whi ch results in lower affinities for guest molecules.