REDUCTIVE REARRANGEMENTS OF SILYLATED PENICILLIN-G 1-OXIDE

Authors
VANDERKLEIN PAM WITKAMP HA DEVROOM E
Citation
Pam. Vanderklein et al., REDUCTIVE REARRANGEMENTS OF SILYLATED PENICILLIN-G 1-OXIDE, Tetrahedron letters, 35(46), 1994, pp. 8691-8692
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
46
Year of publication
1994
Pages
8691 - 8692
Database
ISI
SICI code
0040-4039(1994)35:46<8691:RROSP1>2.0.ZU;2-C
Abstract
The reaction of penicillin G 1-oxide with BSU followed by treatment wi th tributyl phosphite gives, after hydrolysis, crystalline thiazoline azetidinone 2. Addition of triethylamine after reduction resulted in t he formation of the isomeric thiazoline azetidinone 3.