RAPID AND EFFICIENT ENTRY TO SUBSTITUTED 2-SUCCINIMIDOBENZOATE-3-AZABICYCLO[3.3.1]NONANES - AE-BICYCLIC ANALOGS OF METHYLLYCACONITINE

Authors
COATES PA BLAGBROUGH IS ROWAN MG POTTER BVL PEARSON DPJ LEWIS T
Citation
Pa. Coates et al., RAPID AND EFFICIENT ENTRY TO SUBSTITUTED 2-SUCCINIMIDOBENZOATE-3-AZABICYCLO[3.3.1]NONANES - AE-BICYCLIC ANALOGS OF METHYLLYCACONITINE, Tetrahedron letters, 35(46), 1994, pp. 8709-8712
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
46
Year of publication
1994
Pages
8709 - 8712
Database
ISI
SICI code
0040-4039(1994)35:46<8709:RAEETS>2.0.ZU;2-B
Abstract
A double Mannich reaction allows a rapid and efficient entry to substi tuted 3-azabicyclo[3.3.1]nonane analogues of methyllycaconitine (MLA), a selective antagonist of certain mammalian and insect alpha-bungarot oxin-sensitive nicotinic acetylcholine receptors.