Tb. Martins et al., COMPARISON OF 3 COMMERCIALLY AVAILABLE ASSAYS FOR DETECTION OF VARICELLA-ZOSTER VIRUS-ANTIBODY, Clinical and diagnostic laboratory immunology, 1(2), 1994, pp. 186-188
Three commercially available diagnostic assays for the detection of an
tibodies to varicella-zoster virus were evaluated to determine which w
ould be the most suitable for our clinical laboratory. Three different
methods were examined: an enzyme-linked immunosorbent assay (ELISA),
latex agglutination (LA), and an indirect fluorescent-antibody techniq
ue. For the 141 serum specimens tested, the ELISA had an agreement of
90.1% and LA had an agreement of 92.2% with the indirect immunofluores
cent-antibody technique. The ELISA had a lower sensitivity (85.6%) tha
n LA (100.0%), but LA suffered from a low specificity (78.4%) compared
with the ELISA (98.0%).