Mh. Vazquezlevin et al., URINE CONTAMINATION OF SEMINAL FLUID AFTER TRANSURETHRAL RESECTION OFTHE EJACULATORY DUCTS, The Journal of urology, 152(6), 1994, pp. 2049-2052
Transurethral resection of ejaculatory duct obstruction has assumed a
significant role in the treatment of infertile men. The potential impa
ct of disruption of the ejaculatory duct apparatus after transurethral
resection has not been studied. The seminal plasma of patients was ev
aluated after transurethral resection of the ejaculatory ducts by dete
rmining creatinine levels as a measure of urine contamination of semen
. Analysis of semen parameters was retrospectively performed on preope
rative and postoperative samples in 8 subfertile men diagnosed with ej
aculatory duct obstruction treated by transurethral resection. These w
ere not 8 consecutive patients but rather individuals from a larger se
ries who had seminal plasma frozen preoperatively and postoperatively.
A significant increase in seminal plasma creatinine levels postoperat
ively was detected in 7 of 8 patients evaluated. In patients who were
requested to produce 2 specimens within 1 hour high levels of creatini
ne were found in both ejaculates, although creatinine levels were lowe
r in the second ejaculate. The patient who postoperatively had low lev
els of creatinine in seminal plasma demonstrated an improvement in spe
rm concentration and morphology, and his wife became pregnant. Transur
ethral resection of the ejaculatory ducts results in marked improvemen
t in some semen parameters. However, the impact of urine contamination
in semen after transurethral resection of the ejaculatory ducts must
be assessed in the management of patients who present with ejaculatory
duct obstruction.