THE VITEK IMMUNODIAGNOSTIC ASSAY FOR DETECTION OF IMMUNOGLOBULIN-M TOXOPLASMA ANTIBODIES

Authors
CANDOLFI E RAMIREZ R HADJU MP SHUBERT C REMINGTON JS
Citation
E. Candolfi et al., THE VITEK IMMUNODIAGNOSTIC ASSAY FOR DETECTION OF IMMUNOGLOBULIN-M TOXOPLASMA ANTIBODIES, Clinical and diagnostic laboratory immunology, 1(4), 1994, pp. 401-405
Citations number
16
Categorie Soggetti
Immunology,"Infectious Diseases","Medical Laboratory Technology",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
1
Issue
4
Year of publication
1994
Pages
401 - 405
Database
ISI
SICI code
1071-412X(1994)1:4<401:TVIAFD>2.0.ZU;2-R
Abstract
We compared the Vitek immunodiagnostic assay for detection of immunogl obulin M (IgM) toxoplasma antibodies (VIDAS TXM) with an IgM enzyme-li nked immunosorbent assay (ELISA) which we developed. A total of 407 se rum samples from 391 adults were used for this study. We also examined 17 serial serum samples from four women who had seroconverted during gestation. We observed a sensitivity of 99.5%, a specificity of 93%, a positive predictive value of 93.6%, a negative predictive value of 99 .5%, and a global agreement of 96%. In each case of seroconversion the VIDAS TXM became positive at the same time as did the IgM ELISA.