NEAR-INFRARED RAMAN SPECTROMETER SYSTEMS FOR HUMAN TISSUE STUDIES

We have built two types of instruments for near-infrared Raman spectro scopy studies of human tissues, one for laboratory measurements and on e for clinical use. The laboratory systems are designed to collect the highest quality spectra possible and allow different excitation/colle ction wavelengths to be studied. The clinical systems are designed to collect spectra via optical fibers within a few seconds and to be mobi le and hospital-compatible. These systems are capable of detecting wea k near-infrared Raman bands hidden in large background signals. Calibr ation and background subtraction procedures are described, and system performance is evaluated.