NEUROLOGICAL ABNORMALITIES IN PATIENTS WITH SCHIZOPHRENIA OR SCHIZOPHRENIFORM DISORDER AT FIRST ADMISSION TO HOSPITAL - CORRELATIONS WITH COMPUTERIZED-TOMOGRAPHY AND REGIONAL CEREBRAL BLOOD-FLOW FINDINGS

Forty-five patients with schizophrenia or schizophreniform disorder ad mitted to hospital for the first time had a neurological examination, including integrative sensory and complex motor acts, by a trained neu rologist. The patients were studied by CT (computerized tomography) an d rCBF (regional cerebral blood flow) as well. A control group of 24 h ealthy volunteers was included. The patients had significantly more ne urological abnormalities (NA) than the healthy volunteers. Medication did not explain the discrepancy. The NA were associated with sulcal en largement and smaller brains as visualized by CT but not with ventricu lar enlargement. There was no association between the regional flow va lues and NA.