CORRELATION BETWEEN DETECTION OF HERPES-SIMPLEX VIRUS IN ORAL SECRETIONS BY PCR AND SUSCEPTIBILITY TO EXPERIMENTAL UV RADIATION-INDUCED HERPES LABIALIS
Jd. Kriesel et al., CORRELATION BETWEEN DETECTION OF HERPES-SIMPLEX VIRUS IN ORAL SECRETIONS BY PCR AND SUSCEPTIBILITY TO EXPERIMENTAL UV RADIATION-INDUCED HERPES LABIALIS, Journal of clinical microbiology, 32(12), 1994, pp. 3088-3090
We examined the oral secretions of 25 patients for herpes simplex viru
s (HSV) at the time of and following experimental UV radiation (UVR).
HSV was detected in one or more oral secretion specimens in 5 of 12 (4
2%) cases by cell culture and in 8 of 12 (67%) cases by PCR. On the da
y of UVR, HSV was detected in 1 of 12 (8%) patients who developed a li
p lesion and 2 of 16 (13%) patients who did not (the difference is not
significant). We conclude that PCR is more sensitive than culture in
the detection of HSV and that HSV is not shed with increased frequency
from the oral cavity before the development of UVR-induced herpes lab
ialis.