Gl. Viale et al., LONGITUDINAL-STUDY OF CEREBRAL BLOOD PLOW FOLLOWING EARLY OR DELAYED SURGERY FOR RUPTURED INTRACRANIAL ANEURYSMS, Acta neurochirurgica, 131(1-2), 1994, pp. 6-11
Out of a series of 43 cases operated on for ruptured intracranial aneu
rysms over a 12-month-period, 32 patients were followed up to 12 month
s postoperatively with repeated evaluations of cerebral blood flow, us
ing the Xenon(133) inhalation technique. No statistically significant
differences in cerebral perfusion were detected between the subgroups
of good-grade patients, who were submitted respectively to early, or d
elayed surgery. Depression of flow in the affected hemisphere of poor-
grade patients was principally related to the preoperative occurrence
of an intracerebral haematoma. The overall results were not consistent
with the hypothesis that early surgical intervention results in long-
lasting effects on the cerebral circulation.