Brachytherapy using the afterloading technique with iridium 192 and pe
rcutaneous irradiation using 16 MV photons are used for the irradiatio
n of malignant obstructive jaundice. Mostly, however, a combination of
both methods can be used to advantage. In bile duct tumors and Klatsk
in tumors, the endoluminal part can be treated using brachytherapy. Th
e extralumenal growth and, if necessary, all affected regional lymph n
ode areas can be treated by a 3D planned, percutaneous, moving field t
echnique. Intraoperative radiotherapy can be used in a few cases as bo
oster irradiation of tumor conglomerates at the porta hepatis. The dec
ision to use irradiation must be made very carefully since solid tumor
s are usually involved that require a high target dose, the applicatio
n of which can lead to unacceptable side effects. The radio-oncologica
l spectrum is therefore confined predominantly to palliative therapy.