K. Hughes et al., TRICHLOROETHYLENE - EVALUATION OF RISKS TO HEALTH FROM ENVIRONMENTAL EXPOSURE IN CANADA, Environmental carcinogenesis & ecotoxicology reviews, 12(2), 1994, pp. 527-543
In this assessment of trichloroethylene as a Priority Substance under
the Canadian Environmental Protection Act, estimates of the average to
tal daily intake are presented and available data on potential health
effects are evaluated. Although some of the tumours induced in animals
by trichloroethylene may not be relevant to humans, or humans may be
much less sensitive, it was concluded that there was sufficient weight
of evidence to classify trichloroethylene as ''probably carcinogenic
to humans''. Based on comparison of the average daily intake of trichl
oroethylene with the potential of this substance to induce tumours, th
e priority for analysis of options to reduce exposure in the general e
nvironment is considered to be low to moderate compared to that of oth
er substances assessed in the Priority Substances program.