METHOD OF SUPERSELECTIVE RADIO-EMBOLIZATI ON OF LIVER-TUMORS WITH (90)YTTRIUM-RESIN PARTICLES

An improved technique for radioembolisation of non-resectabIe liver tu mours is described. (90)Yttrium-labelled Bio-Rex-70 particles which sh ow high stability and good tissue tolerance are applied superselective ly via the tumour-feeding artery using a microcatheter The procedure i ncludes both diagnostic and therapeutic angiography. Angiography is co mplemented by angioscintigraphy (Tc-99m-MAP) and an i.v. Tc-99m-colloi d scan of the liver. Thus it is possible pretherapeutically to evaluat e tumour volume and dose distribution both in and outside of the liver , and in the lung due to shunt. These estimates were re-evaluated post therapeutically. Radioembolisation can thus be quantified and the dose s absorbed by the tumour as well as the liver and lung can be calculat ed.