EFFECTS OF DIETARY THERAPY ON POST RENAL-TRANSPLANT HYPERLIPIDEMIA - A PROSPECTIVE-STUDY

Hyperlipidemia often occurs after renal transplantation and may contri bute to increased cardiovascular morbidity. The National cholesterol e ducation program guidelines (NCEP) recommend dietary modification as t he initial therapeutic intervention. We evaluated the effects of the A HA Step I and Step II diets on the serum total cholesterol (TC) and th e triglyceride (TG) levels in nondiabetic renal transplant patients. B oth the AHA Step I (TC 296 +/- 7 vs 294 +/- 9 mg/dL, p = ns) and Step II diets (TC 282 +/- 8 vs 292 +/- 16 mg/dL; p = ns) failed to signific antly lower the serum fetal cholesterol and the triglycerides levels. During this dietary intervention, the patients' body weight and serum creatinine level remained stable. Our data suggest that neither the AH A Step I nor the Step II diet are effective in significantly lowering elevated serum lipids in nondiabetic renal transplant recipients.