SEROVARS AND MULTIPLE-DRUG RESISTANT SALMONELLA SP ISOLATED FROM CHILDREN IN RIO-DE-JANEIRO BRAZIL

The Serological characterization and antimicrobial susceptibility of 1 16 Salmonella strains were studied. These isolates were obtained from stool and blood specimens of children who received treatment at the In stitute Fernandes Figueira, FIOCRUZ (Rio de Janeiro, Brazil) between M ay 1987 and July 1992.Six serogroups (04; 07; 08; 09; 03,10 and 035) a nd 18 serovars were detected, the highest frequency being observed for S.typhimurium (62.93%) and S.agona (7.75%). Antimicrobial susceptibil ity was tested for ampicillin (Ap), cephalotin (Cf), cefoxitin (Cx), c eftriaxone (Cro), pefloxacin (Pf), gentamicin (Ge),amikacin (Am), sulf amethoxazole-trimethoprim (SxT),chloramphenicol (Cl) and tetracyclin ( Te). 92.52% of the S.typhimurium isolates had resistance determinants. Twenty-nine patterns of resistance were encountered; the most frequen t were AD, Cf, Pf, Ge, Am, SxT, Cl, Te for S.typhimurium (40.57%) and Te for the other serovars (20.83%). The minimum inhibitory concentrati on analysis of five antimicrobials showed high levels of resistance to Ap and Cl and low levels of resistance to Ge, SxT and Cro.