PENICILLIN-RESISTANT STREPTOCOCCUS-PNEUMONIAE FROM PATIENTS WITH MENINGITIS

The susceptibility to antibiotics of 146 strains of Streptococcus pneu moniae isolate from cerebrospinal fluid (CSF) was studied. Seven strai ns, 3 of the resistant and 4 of the moderately susceptible phenotype, showed similar results for oxacillin by the disk diffusion method and for penicillin by the minimal inhibitory concentration method. Two str ains showed opposite results when comparing the two methods. All the o ther strains (137) were inhibited at an oxacillin concentration of 1 u g/ml by the diffusion disk test.