SEQUENCES OF CDNAS ENCODING IMMUNOGLOBULIN HEAVY-CHAIN AND LIGHT-CHAIN VARIABLE REGIONS FROM 2 ANTI-DIOXIN MONOCLONAL-ANTIBODIES

Authors
RECINOS A SILVEY KJ OW DJ JENSEN RH STANKER LH
Citation
A. Recinos et al., SEQUENCES OF CDNAS ENCODING IMMUNOGLOBULIN HEAVY-CHAIN AND LIGHT-CHAIN VARIABLE REGIONS FROM 2 ANTI-DIOXIN MONOCLONAL-ANTIBODIES, Gene, 149(2), 1994, pp. 385-386
Citations number
3
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
149
Issue
2
Year of publication
1994
Pages
385 - 386
Database
ISI
SICI code
0378-1119(1994)149:2<385:SOCEIH>2.0.ZU;2-E
Abstract
We report the cDNA cloning of the gamma- and kappa-chain-encoding gene s for two mouse monoclonal antibodies (mAb) which recognize dioxins. T he nucleotide sequences encoding the variable regions of these mAb wer e also determined. Although the mAb have similar dioxin-binding charac teristics, their deduced variable region amino-acid sequences are very different.