MANAGEMENT OF DISSEMINATED KIDNEY CANCER

The approach to disseminate renal cell carcinoma (RCC) has evolved sig nificantly in recent years, largely owing to the progress of biologic therapy development. With increasing knowledge of biologic therapy com e several dilemmas, including the choice of cytokine therapy, the appr opriate mode of delivery, the selection of candidates for given therap eutic options, and the role of cytoreductive nephrectomy in immunother apy protocols. This article reviews the historical development of immu notherapy and the lessons learned from previous experience and offers a logical approach to the patient with disseminated RCC.