2 MOSAIC-YY MALES CARRYING ASYMMETRIC Y-CHROMOSOMES

Authors
ZELANTE L DALLAPICCOLA B CALVANO S MEMEO E GASPARINI P SIMI P ROSSI S FINELLI P ROCCHI M ARCHIDIACONO N
Citation
L. Zelante et al., 2 MOSAIC-YY MALES CARRYING ASYMMETRIC Y-CHROMOSOMES, Clinical genetics, 51(1), 1997, pp. 65-68
Citations number
15
Categorie Soggetti
Genetics & Heredity
Journal title
Clinical genetics → ACNP
ISSN journal
00099163
Volume
51
Issue
1
Year of publication
1997
Pages
65 - 68
Database
ISI
SICI code
0009-9163(1997)51:1<65:2MMCAY>2.0.ZU;2-5
Abstract
Two patients were referred because of oligospermia and azospermia, res pectively. Karyotypic analysis revealed two mosaic-YY males carrying a symmetric Y chromosomes. To our knowledge, no instance of double unequ al Y chromosomes has been reported so far in human males. Results of f luorescent in situ hybridization (FISH) studies in spermatozoa from on e of these patients revealed a significantly high number of hyperaploi d spermatozoa.