SYNTHESIS OF SOME 4-THIAZOLINE AND 4H-1,2,4-TRIAZOLE DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE AS POSSIBLE ANTICONVULSANTS

Authors
CESUR N CESUR Z
Citation
N. Cesur et Z. Cesur, SYNTHESIS OF SOME 4-THIAZOLINE AND 4H-1,2,4-TRIAZOLE DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE AS POSSIBLE ANTICONVULSANTS, Il Farmaco, 49(10), 1994, pp. 679-681
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
49
Issue
10
Year of publication
1994
Pages
679 - 681
Database
ISI
SICI code
0014-827X(1994)49:10<679:SOS4A4>2.0.ZU;2-X
Abstract
Several limidazo[1,2-a]pyridine-3-yl)carbonyl]hydrazono-3- nonsubstitu ted/substituted-4-phenyl-4-thiazolines (3a-d, 3f-h) and 3-(2-methylimi dazo[1,2-a] -3-yl)-4-nonsubstituted/substituted-5-mercapto-4H- 1,2,4-t riazoles(4a-f, 4i) were synthesized, characterized and evaluated for a nticonvulsant activity. Only 3g showed significant activity against ME S induced seizures.