Pulmonary edema is caused by transudation of fluid from pulmonary capi
llaries into the alveolar spaces and the bronchiolus. It is most frequ
ently secondary to either increased pulmonary capillary hydrostatic pr
essure (cardiogenic pulmonary edema) or increased pulmonary capillary
permeability (noncardiogenic pulmonary edema). Numerous systemic and p
ulmonary insults are capable of damaging the capillary endothelium and
/or alveolar epithelium, resulting in noncardiogenic pulmonary edema.
Although clinically similar, the presence of noncardiogenic pulmonary
edema requires a different therapeutic approach from that of cardiogen
ic pulmonary edema.