Thymus glands of two salmonid species, Salmo trutta and Oncorhynchus m
ykiss, caught monthly throughout the year, were examined by light and
transmission electron microscopy. Erythropoietic foci, consisting of b
oth developing and mature erythroid cells, occurred in the subcapsular
, inner, and outer thymic zones from April to November. We discuss the
possible physiological significance of this seasonal erythropoietic a
ctivity, together with the role played by the thymic cell microenviron
ments and endocrine factors.