Tap water iontophoresis is the therapy of choice in hyperhidrosis palm
oplantaris. Therapeutic regimens, however, vary greatly. The aim of th
e present study was to develop an optimized therapeutic scheme. The ma
in methodologic parameters subjected to systematic experimental study
included the effects of current polarity, the duration of a single tre
atment session, the addition of electrolytes to the tap water and the
treatment interval during maintenance therapy. The following procedure
is proposed. During the initial phase, treatments are carried out thr
ee times weekly for 10 min each time. The anode is kept on one extremi
ty until normhidrosis is reached on this extremity. Then, polarity is
changed until sweating is reduced to normal on the other extremity (co
nstant polarity). In the subsequent maintenance phase, patients are tr
eated at intervals of 6-8 days for 10 min each time. Polarity is switc
hed from treatment to treatment (alternating polarity). Plain tap wate
r is used without additives.