BRDU INCORPORATION REVEALS DNA-REPLICATION IN NON DIVIDING GLIAL-CELLS IN THE LARVAL ABDOMINAL CNS OF DROSOPHILA

Citation
A. Prokop et Gm. Technau, BRDU INCORPORATION REVEALS DNA-REPLICATION IN NON DIVIDING GLIAL-CELLS IN THE LARVAL ABDOMINAL CNS OF DROSOPHILA, Roux's archives of developmental biology, 204(1), 1994, pp. 54-61
Citations number
47
Categorie Soggetti
Developmental Biology
ISSN journal
0930035X
Volume
204
Issue
1
Year of publication
1994
Pages
54 - 61
Database
ISI
SICI code
0930-035X(1994)204:1<54:BIRDIN>2.0.ZU;2-6
Abstract
Glial cells are of significant importance for central nervous system d evelopment and function. In in sects, knowledge of the types and devel opment of CNS glia is rather low. This is especially true for postembr yonic glial development. Using bromodeoxyuridine incorporation and enh ancer trap lines we identified a reproducible spatial and temporal pat tern of DNA replicating cells in the abdominal larval CNS (A3-7 neurom eres) of Drosophila melanogaster. These cells correspond to em bryonic ally established glial cells in that region. Except for a specific sub fraction, these cells apparently do not divide during larval life. Sim ilar patterns were found in two other Drosophila species, D. virilis a nd D. hydei.