THEORY OF ONCOGENE ACTIVATION BY CHEMICALS AND ANTIONCOGENE INACTIVATION BY RADIATIONS - POSSIBLE CARCINOGENIC EFFECT OF POWER-LINES

Authors
Citation
Jj. Ladik, THEORY OF ONCOGENE ACTIVATION BY CHEMICALS AND ANTIONCOGENE INACTIVATION BY RADIATIONS - POSSIBLE CARCINOGENIC EFFECT OF POWER-LINES, International journal of oncology, 5(6), 1994, pp. 1459-1462
Citations number
18
Categorie Soggetti
Oncology
ISSN journal
10196439
Volume
5
Issue
6
Year of publication
1994
Pages
1459 - 1462
Database
ISI
SICI code
1019-6439(1994)5:6<1459:TOOABC>2.0.ZU;2-A
Abstract
To activate the cancerous information present in every cell one has ei ther to activate oncogenes or to inactivate antioncogenes. This happen s in the cell with the aid of external factors, especially chemical ca rcinogens and radiations. Simple statistical considerations have shown that both oncogene activation by chemical carcinogens and double stra nd breaks by ionizing radiations leading to antioncogene inactivation are not caused only by local effects. Different mechanisms were invest igated to prove the role of long-range effects of carcinogens in initi ating the malignant transformation of an eucaryotic cell. Finally, on the basis of very sound theoretical correlations it is shown that neit her high voltage power lines nor TV sets, terminals and other electric household appliances are hazardous for human health (and they are not causing cancer).