The synthesis of polymeric membranes that exhibit high permeation sele
ctivity and high flux is a major challenge that has important technolo
gical implications. In an effort to rationally design such materials,
the concept of perforated monolayers (i.e., two-dimensional arrays of
porous surfactants) has been introduced. Results that have been obtain
ed to date, using prototype systems, provide considerable incentive fo
r exploring and exploiting such ultrathin materials as novel membranes
for separation.