MULTIPLE PERIFOLLICULAR FIBROMAS - REPORT OF A CASE AND ANALYSIS OF THE LITERATURE

Perifollicular fibroma is a cutaneous hamartomatous proliferation of t he pilar connective tissue sheath. Mie describe a patient with multipl e perifollicular fibromas and analyze the literature on this topic. Hi stologically, perifollicular fibroma is characterized by a concentric arrangement of collagen fibers surrounding a generally unaltered hair follicle. Clinically, it is usually multiple and occurs predominantly on the face and upper trunk. This clinical presentation is similar to that observed in patients with the Birt-Hogg-Dube syndrome where, in a ddition to perifollicular fibromas, fibrofolliculomas, trichodiscomas, and acrochordons are found. Several reports of multiple perifollicula r fibroma prior to the recognition of this syndrome may, in fact, repr esent cases of the Birt-Hogg-Dube syndrome.