STEREOSELECTIVE SYNTHESIS OF BETA-AMINO HYDROXYLAMINES

Authors
REETZ MT ROHRIG D HARMS K FRENKING G
Citation
Mt. Reetz et al., STEREOSELECTIVE SYNTHESIS OF BETA-AMINO HYDROXYLAMINES, Tetrahedron letters, 35(47), 1994, pp. 8765-8768
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
47
Year of publication
1994
Pages
8765 - 8768
Database
ISI
SICI code
0040-4039(1994)35:47<8765:SSOBH>2.0.ZU;2-B
Abstract
Chiral gamma-N,N-dibenzylamino-substituted alpha,beta-unsaturated carb oxylic acid esters and dicarboxylic acid esters, prepared in enantiome rically pure form from L-amino acids, under go diastereoselective Mich ael addition reactions with nitrogen nucleophiles of the type Me(3)SiN HOSiMe(3) and CH3NNOH; the products are novel beta-amino hydroxylamine derivatives having two defined stereogenic centers.