PRELACINAN-7-OL, A NOVEL SESQUITERPENE FROM RUDBECKIA-LACINIATA

Authors
FUKUSHI Y YAJIMA C MIZUTANI J
Citation
Y. Fukushi et al., PRELACINAN-7-OL, A NOVEL SESQUITERPENE FROM RUDBECKIA-LACINIATA, Tetrahedron letters, 35(47), 1994, pp. 8809-8812
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
47
Year of publication
1994
Pages
8809 - 8812
Database
ISI
SICI code
0040-4039(1994)35:47<8809:PANSFR>2.0.ZU;2-C
Abstract
A new tricyclic sesquiterpene. prelacinan-7-ol (1) was isolated from t he roots of Rudbeckia laciniata. The structure was determined on the b ase of the extensive 2D NMR analyses. The absolute configuration was e stablished by derivatizing to axially chiral 2-(2'-methoxy-1'-naphthyl )-3,5-dichlorobenzoic acid (MNCB, 3) and 2'-methoxy-1,1'-binaphthyl-2- carboxylic acid (MBNC, 4) esters. For the same purpose, ''Modified Mos her's method'' was inapplicable.