XENIAFARAUNOL-A AND XENIAFARAUNOL-B, AND FARAUNATIN - 3 NEW CYTOTOXICDITERPENES FROM THE SOFT CORAL XENIA-FARAUNENSIS

Authors
KASHMAN Y SALTOUN M RUDI A BENAYAHU Y
Citation
Y. Kashman et al., XENIAFARAUNOL-A AND XENIAFARAUNOL-B, AND FARAUNATIN - 3 NEW CYTOTOXICDITERPENES FROM THE SOFT CORAL XENIA-FARAUNENSIS, Tetrahedron letters, 35(47), 1994, pp. 8855-8858
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
47
Year of publication
1994
Pages
8855 - 8858
Database
ISI
SICI code
0040-4039(1994)35:47<8855:XAXAF->2.0.ZU;2-A
Abstract
The organic extract of Xenia faraunensis was found to contain besides xeniolide A and B three novel diterpenes: xeniafaraunol A (1), -B (2) and faraunatin (3). The structure of compounds 1-3 was defined by spec tral methods and mainly 1D and 2D NMR experiments. Xeniafaraunol A and B (1 and 2) are of a novel bicyclo[7.4.0] tridecane carbon skeleton a nd faraunatin (3) is an unprecedented prenylated bicyclogermacrene. Co mpounds 1-3 are cytotoxic against P388 cells.