DETERMINATION OF IDPH-8261, A NEW NONSTEROIDAL ANTIINFLAMMATORY DRUG USING ORTHOGONAL POLYNOMIAL FUNCTION

Authors
MARWAH AK VATSA D MARWAH P RAO GS TRIVEDI BS RAGHUVEER S RAO BE
Citation
Ak. Marwah et al., DETERMINATION OF IDPH-8261, A NEW NONSTEROIDAL ANTIINFLAMMATORY DRUG USING ORTHOGONAL POLYNOMIAL FUNCTION, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 33(12), 1994, pp. 1209-1211
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry → ACNP
ISSN journal
03764699
Volume
33
Issue
12
Year of publication
1994
Pages
1209 - 1211
Database
ISI
SICI code
0376-4699(1994)33:12<1209:DOIANN>2.0.ZU;2-1
Abstract
Glenn's method of orthogonal polynomial coefficient is described for t he determination of IDPH-8261 (methyl alpha-methyl-4-(3-thienyl)benzen e acetate), a potent nonsteroidal antiinflammatory agent developed by IDPL Research Centre, Hyderabad, India. The quadratic polynomial coeff icient has been found to bear a linear relation in the concentration r ange of 2 to 20 mcg per ml of the drug, whereby the absorbance has bee n measured at eight points equally spaced at 4 nm interval over the wa velength range of 252 to 280 nm.