Ae. Lang et al., STRIATONIGRAL DEGENERATION - IRON DEPOSITION IN PUTAMEN CORRELATES WITH THE SLIT-LIKE VOID SIGNAL OF MAGNETIC-RESONANCE-IMAGING, Canadian journal of neurological sciences, 21(4), 1994, pp. 311-318
We report three patients with striatonigral degeneration highlighting
the correlation between magnetic resonance imaging (MRI) and the patho
logical changes. The ''slit-like void signal'' observed in the putamen
is typical of striatonigral degeneration and can be used to assist di
agnosis during life. Our histochemical studies support the concept tha
t increased iron deposition in the putamen is responsible for this MRI
picture.