CHIRAL LIGANDS CONTAINING HETEROATOMS .13. OPTICALLY-ACTIVE 4-(2'-PYRIDYL)-1,3-OXAZOLIDINES - AN IMPROVED SYNTHESIS OF 2-(2'-PYRIDYL)-2-AMINOALCOHOLS

Authors
CONTI S COSSU S GIACOMELLI G FALORNI M
Citation
S. Conti et al., CHIRAL LIGANDS CONTAINING HETEROATOMS .13. OPTICALLY-ACTIVE 4-(2'-PYRIDYL)-1,3-OXAZOLIDINES - AN IMPROVED SYNTHESIS OF 2-(2'-PYRIDYL)-2-AMINOALCOHOLS, Tetrahedron, 50(47), 1994, pp. 13493-13500
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
47
Year of publication
1994
Pages
13493 - 13500
Database
ISI
SICI code
0040-4020(1994)50:47<13493:CLCH.O>2.0.ZU;2-N
Abstract
An improved synthesis of 2-(2'-pyridyl)-2-aminoalcohols 1a and 1b, in enantiomerically pure form via 1,3-oxazolidine derivatives is presente d. Some efficient and selective methods for both the cleavage of the o xazolidine ring and the removal of the N-Boc protecting group are also reported.