QUANTITATIVE-ANALYSIS OF TECHNETIUM-99M-METHYLENE DIPHOSPHONATE UPTAKE IN UNILATERAL HYDROXYAPATITE-COATED TOTAL HIP PROSTHESES - FIRST YEAR OF FOLLOW-UP
Aia. Rahmy et al., QUANTITATIVE-ANALYSIS OF TECHNETIUM-99M-METHYLENE DIPHOSPHONATE UPTAKE IN UNILATERAL HYDROXYAPATITE-COATED TOTAL HIP PROSTHESES - FIRST YEAR OF FOLLOW-UP, The Journal of nuclear medicine, 35(11), 1994, pp. 1788-1791
A prospective study was performed on 80 patients who had undergone a u
nilateral hydroxyapatite (HA)-coated total hip arthroplasty to establi
sh the normal periprosthetic uptake of methylenediphosphonate (MDP) as
a function of implant age. Methods: Patients were imaged periodically
while they were asymptomatic at 1, 3, 6 and 12 mo postoperatively. Qa
ntitative measurements were performed with a region of interest (ROI)
technique. The HA-coated and uncoated areas were marked in comparison
with the normal contralateral femur. The uptake ratios of the MDP were
determined postoperatively in the following 12 mo. Results: It was fo
und that a decrease of the uptake ratios occurred in all ROIs. However
, for the HA-coated areas, the uptake ratios still remained raised as
a result of bony ingrowth. Conclusion: The results of the first year o
f follow-up were considered to be a normal database that will be used
as a reference when the same group of patients are followed up to 5 yr
postoperatively to detect any potential modes of failure of the impla
nt.