DETECTION OF MULTIPLE THROMBOEMBOLISM IN CONGENITAL ANTITHROMBIN-III DEFICIENCY WITH INDIUM-121-PLATELET SCINTIGRAPHY

Congenital deficiency of antithrombin III (AT III), a physiological in hibitor of blood coagulation, may lead to increased thromboembolism. H ere, we report a case of multiple thromboembolism associated with cong enital AT III deficiency. The diagnosis of systemic thromboembolism wa s made by In-111-labeled platelet scintigraphy (In-scan) which allowed for the daily assessment of thromboemboli size. Thromboemboli were fo und not only in sites predicted clinically, but also in unexpected sit es. In these patients, thus, a careful whole-body examination is neces sary for full detection of thromboemboli. In-scan may be a useful tech nique for such screening.